olivactive® is an olive leaves extract, natural source of Oleuropein, standardized by HPLC.
oliveactive® is recommended to strengthen the immune system and relieve fatige in case if infection (Lee-Huang, et al., 2003). Olivactive increases teh physiological resistance of the organism in case of severe environmental conditions due to the presence of Oleuropein (Figure1).
Patients with abnormal antioxidant status or high oxidative stress in special cases such as diabetes, leads to tissue damage, with lipid peroxidation, inactivation of proteins, and protein glycation as intermediate mechanisms for complications including retinopathy, nephropathy, and coronary heart disease.
The higher oxidative stress may affect the Immune System, and therefore increases the amount of infections in patients with Diabetes Mellitus. Some microorganisms become more virulent in a high glucose environment, also an increased adherence of microorganisms to diabetic compared to nondiabetic cells occurs.
It has been postulated that supplementation with dietary antioxidant compounds may offer some protection against these complications through their roles as inhibitors of glycation and as free radical scavengers. Recent interests were also in the use of non-vitamin antioxidants such as flavonoids and polyphenols in reducing the negative effect of oxidative stress and free radicals in diabetic patients.
Studies have shown that oleuropein possesses a wide range of pharmacologic and health promoting properties, chiefly immune-stimulant. In fact, oleuropein has antioxidant and anti-in-flammatory activities that strengthen the immune system and relieves chronic fatigue because of the phagocytosis stimulation performed by Oleuropein.
The olive leaves have been used for thousands of years as a natural remedy for the treatment of different diseases in the mediterranean culture (Agalias et al., 2005), and in the recent years, the scientific community has shown a great interes because of the health benefits the publication of several scientific studies:
Luteolin and Luteolin-7-o-glucoside can achieve 100% of inhibitory activity of α-glucosidase and α-amilase at certain concentration (Michelle de Sales et al., 2002; Kim et al., 2014; Ito & Takeda, 2013).
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